NEUROBIOTIN-Plus
Code produit : VEC.SP-1150
VEC.SP-1150Investigators have identified rapid degradation of injected tracers such as biocytin due to the presence of biotinidase activity in brain…
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NEUROBIOTIN-Plus
Product Description
Investigators have identified rapid degradation of injected tracers such as biocytin due to the presence of biotinidase activity in brain tissue*. This loss of stability of the tracer significantly reduces the viable postinjection period and may compromise complete detection of a neural network. NEUROBIOTIN™ -Plus was designed to be impervious to cleavage and breakdown by biotinidase. This newly synthesized biotin-containing compound contains fixable amine groups, is highly soluble and has a low molecular weight. These characteristics make it an ideal candidate for experiments requiring long postinjection survival times and optimal uptake along the entire neural tract.
NEUROBIOTIN™ -Plus shares the same key advantages of NEUROBIOTIN™ Tracer over biocytin and other neuronal labels:
- Better solubility
- More efficiently iontophoresed
- Remains in cell longer
- Non-toxic
- Can be fixed with formalin or glutaraldehyde/li>
NEUROBIOTIN™ -Plus can be detected using avidin or streptavidin systems with either chromogenic or fluorescence visualization methods.
*Mishra, A. et al (2010) ACS Chem. Neurosci. 1:129-138.
NEUROBIOTIN-Plus
Spécifications du produit
Packaging Unit
5 mg
Brand
Vector Laboratories
NEUROBIOTIN-Plus
Documents de produit